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September 2026

All 430 conditions mapped

PLAB Revisions · Neurology · Question 23 of 50

Example
PLAB 1Neurology01:12

A 62-year-old man with atrial fibrillation has had sudden left-sided weakness for 2 hours. CT head shows no haemorrhage. What is the most appropriate immediate management?

  • AAspirin 300 mg
  • BAlteplase (IV thrombolysis)
  • CApixaban 5 mg twice daily
  • DHeparin infusion
  • EObserve and repeat CT in 24 hours
Alteplase is first-line within 4.5 hours once haemorrhage is excluded. Anticoagulation for AF is not started acutely. Thrombectomy is added if imaging shows a large vessel occlusion.NICE NG128
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Question Practice
Emergency medicineQ 42 of 142

A 74-year-old man is brought to the emergency department after collapsing at home. He has atrial fibrillation and takes warfarin. His Glasgow Coma Scale score has fallen from 14 to 10 in the ambulance. Non-contrast CT of the head shows a large left intracerebral haemorrhage. His INR is 3.4. He is not taking antiplatelets. Blood pressure is 168/94 mmHg. There is no history of head trauma. What is the most appropriate immediate pharmacological management of his coagulopathy?

AFresh frozen plasma only
BIntravenous vitamin K only
CFour-factor prothrombin complex concentrate plus intravenous vitamin K
DTranexamic acid only
EPlatelet transfusion

Guideline-aligned explanation

This is the NICE NG128 sequence for intracerebral haemorrhage in a patient taking a vitamin K antagonist with a raised INR: reverse promptly with four-factor PCC and give intravenous vitamin K so the INR does not rebound when the PCC wears off.

NICE NG128RCP 2024
Example

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UKMLA AKT

For UK final-year medical students sitting the Applied Knowledge Test.

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MLA Content Map

Coverage overview

MLA Content Map 2026

2026 Standard
Cardiovascular142 topics

95%

Respiratory118 topics

92%

Gastroenterology104 topics

90%

Neurology96 topics

88%

Musculoskeletal82 topics

85%

Endocrinology78 topics

91%

Renal & Urology74 topics

87%

Psychiatry68 topics

93%

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PLAB 2 · Station 4 · History

PLAB 2 · Station 4 · History

8:00

  • You

    Can you tell me what brought you in today?

OSCE Revisions

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AMC Clinical station

AMC Clinical station

Australian guidelines: RACGP · eTG

Patient: 45-year-old with knee pain. Task: take a focused history and explain the next steps.

Reading time 2:00

8:00

Example

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    Heart failure — immediate management

    NICE NG106

    Key points

    • First-line: ACEi + β-blocker (titrate to target dose)
    • Add MRA if symptoms persist (NYHA II–IV with LVEF ≤35%)
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    ⚡

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    💡

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    Last reviewed 14 Mar 2026✓ NICE verified
    Example
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PLAB 2 · Station 4 · History

PLAB 2 · Station 4 · History

8:00

  • You

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  • Patient

    I've had a tight pain in the centre of my chest since this morning.

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Example feedback

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July 19, 2026

Introducing OSCE Revisions: the clinical exam, finally done properly

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Your Personal 1-on-1 Medical Tutor: Master the PLAB & UKMLA Exam or improve your clinicals with AI

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November 2025 PLAB & UKMLA Exam Update: Latest Questions, Key Changes, and Expert Insights

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August 2025 PLAB & UKMLA Exam Update: Latest Questions, Key Changes, and Expert Insights

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May 2025 PLAB & UKMLA Exam Update: Latest Questions, New Topics, and Platform Highlights

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What is the PLAB 1 exam?

PLAB 1 is the written part of the GMC's Professional and Linguistic Assessments Board test for international medical graduates. It is a 3-hour paper of 180 single-best-answer questions, set against the MLA content map.

How do I book PLAB 1?

Create a GMC Online account, have your English language evidence accepted, and book a seat in GMC Online when places are released. Our PLAB 1 exam dates 2026 page tracks every sitting.

When will I get my PLAB 1 results?

The GMC publishes a results date for each sitting, usually about six weeks after the exam. You'll see your result in GMC Online.

What is the pass mark for PLAB 1?

The pass mark is set separately for each sitting through standard setting, so it changes slightly each time. The GMC publishes it with the results.

What does PLAB 1 cover?

PLAB 1 is set against the GMC's MLA content map, which lists the conditions and presentations a new UK doctor must know. See our UKMLA content map explained guide.

How should I prepare for PLAB 1?

Start with Study Essential mode to cover the content map, practise with exam-style questions and timed mocks, and book when your Readiness Score is consistently in the passing range. Our 3-month study plan shows the week-by-week approach.

Can I cancel my PLAB 1 booking?

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